I don't think it is anything you need to worry about, I have been using Intel SSD's without issue for more than 12 months - having just checked, they still show 100% life remaining.
Under normal conditions Mach3 will not write to the HDD/SSD during runtime when using the parallel port for machine communication.
However, when using an external motion controller the Mach3 .xml file can, and often is written to during configuration parameter changes.
Tweakie.