Ok first thing is Ports and Pins, Motor Outputs, you have Spindle set to Pin 10 for step, you cant have that as it is an input pin and I think you control the spindle on/off manually anyway so just disable spindle all together on that page if that is the case. Next on your outputs page you have Output 2 set to Pin 10, you cant have that as previously mentioned it is an input pin, just place 0 in that box instead, same goes for Outut 1, you can just enter 0 for that as well as I dont think you are using it.
See how you go with changing these settings and also remember to tell Mach the spindle has started (M3 in code or press Spindle button) and hopefully you will see a spindle speed and threading will work
Hood